Guo GY., Ebihara K., Fujiwara H.*, Toume K., Awale S., Araki R., Yabe T., Dong E., Matsumoto K. (2019) Kami-shoyo-san ameliorates sociability deficits in ovariectomized mice, a putative female model of autism spectrum disorder, via facilitating dopamine D1 and GABAA receptor functions. J Ethnopharmacol. 236: 231-239.
Guo GY., Ebihara K., Shimodaira T., Fujiwara H.*, Toume K., Dibwe DF., Awale S., Araki R., Yabe T., Matsumoto K. (2019) Kami-shoyo-san improves ASD-like behaviors caused by decreasing allopregnanolone biosynthesis in an SKF mouse model of autism. PLOS One 14: e0211266, doi: 10.1371/journal.pone.0211266.
Fujiwara H.*, Yoshida J., Dibwe DF., Awale S., Hoshino H., Kohama H., Arai H., Kudo Y., Matsumoto K. (2019) Orengedokuto and san'oshashinto improve memory deficits by inhibiting aging-dependent activation of glycogen synthase kinase-3β. J Tradit Complement Med. doi: 10.1016/j.jtcme.2018.12.001.
Kimura K., Matsumoto K., Ohtake H., Oka J.I., Fujiwara H.* (2018) Endogenous acetylcholine regulates neuronal and astrocytic vascular endothelial growth factor expression levels via different acetylcholine receptor mechanisms. Neurochem Int. 118: 42-51.
Fujiwara H.*, Tsushima R., Okada R., Awale S., Araki R., Yabe T., Matsumoto K. (2018) Sansoninto, a traditional herbal medicine, ameliorates behavioral abnormalities and down-regulation of early growth response-1 expression in mice exposed to social isolation stress. J Tradit Complement Med. 8: 81-88.
Ebihara K., Fujiwara H.*, Awale S, Dibwe DF., Araki R., Yabe T., Matsumto K.* (2017) Decrease in endogenous brain allopregnanolone induces autism spectrum disorder (ASD)-like behavior in mice: a novel animal model of ASD. Behav Brain Res. 334: 6-15.
Fujiwara H.*, Han Y., Ebihara K., Awale S., Araki R., Yabe T., Matsumoto K. (2017) Daily administration of yokukansan and keishito prevents social isolation-induced behavioral abnormalities and down-regulation of phosphorylation of neuroplasticity-related signaling molecules in mice. BMC Complement Altern Med. 17: 195 DOI 10.1186/s12906-017-1710-7.